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鲁义善，博士，教授，博士生导师/硕士生导师。广东省“千百十”工程省级培养对象，深圳市地方级领军人才，全国首席科学传播专家，国际食品法典（CAC）抗菌素耐药专家委员会委员，全国水产品质量安全专家工作组成员，农业部水产养殖病害防治专家委员会委员，全国兽药残留与耐药性控制专家委员，挪威特罗姆瑟大学渔业科学学院访问学者。现为广东省水生动物健康评估工程技术研究中心主任，广东省教育厅 “广东海洋大学-英国斯特灵大学渔用疫苗实用化技术”国际合作平台负责人，深圳市海水经济动物种苗健康评价公共技术服务平台主任。近年来主持国家自然科学基金2项、省部级项目7项；参... 详细>>

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共 223 条记录，以下是 1-30

A review on the application of Bacillus as probiotics in aquaculture: FISH & SHELLFISH IMMUNOLOGYKuebutornye, Felix K. A. Abarike, Emmanuel Delwin Lu, Yishan 出版年：2019; Probiotics use in aquaculture has gained attention as microbial candidates to maintain the health and the wellbeing of many aquaculture animals. Among the many microbial candidates, probiotic Bacillus has sporulation cap...

Effects of a commercial probiotic BS containing Bacillus subtilis and Bacillus licheniformis on growth, immune response and disease resistance in Nile tilapia, Oreochromis niloticus: FISH & SHELLFISH IMMUNOLOGYAbarike, Emmanuel Delwin Cai, Jia Lu, Yishan Yu, Huang Chen, Lihua Jian, Jichang Tang, Jufen Jun, Liang Kuebutornye, Felix K. A. 出版年：2018; The present study evaluated a commercial probiotic designated as BS (a mix of B. subtilis and B. licheniformis) to ascertain its efficacy and the dose necessary to improve growth, immune response, and disease resistance ...

The use of Bacillus species in maintenance of water quality in aquaculture: A review: AQUACULTURE REPORTSHlordzi, Vivian Kuebutornye, Felix K. A. Afriyie, Gyamfua Abarike, Emmanuel Delwin Lu, Yishan Chi, Shuyan Anokyewaa, Melody A. 出版年：2020; Aquaculture effluent is often associated with increased organic carbon, suspended solids, phosphates, nitrogenous species (nitrates, nitrites, and ammonia), chemical oxygen demand and biological oxygen demand. This is re...

Mechanisms and the role of probiotic Bacillus in mitigating fish pathogens in aquaculture: FISH PHYSIOLOGY AND BIOCHEMISTRYKuebutornye, Felix K. A. Abarike, Emmanuel Delwin Lu, Yishan Hlordzi, Vivian Sakyi, Michael Essien Afriyie, Gyamfua Wang, Zhiwen Li, Yuan Xie, Cai Xia 出版年：2020; Diseases are natural components of the environment, and many have economic implications for aquaculture and fisheries. Aquaculture is a fast-growing industry with the aim to meet the high protein demand of the ever-incre...

Cloning and expression of heat shock protein 70 gene in the haemocytes of pearl oyster (Pinctada fucata, Gould 1850) responding to bacterial challenge: FISH & SHELLFISH IMMUNOLOGYWang, Zhongliang Wu, Zaohe Jian, Jichang Lu, Yishan 出版年：2009; The cDNA of pearl oyster Pinctada fucata Hsp70 (designated PFHsp70) was cloned by EST and rapid amplification of cDNA ends (RACE) techniques. The full length of PFHsp70 cDNA was 2376 bp, consisting of a 5'-terminal untra...

Effects of three host-associated Bacillus species on mucosal immunity and gut health of Nile tilapia, Oreochromis niloticus and its resistance against Aeromonas hydrophila infection: FISH & SHELLFISH IMMUNOLOGYKuebutornye, Felix K. A. Wang, Zhiwen Lu, Yishan Abarike, Emmanuel Delwin Sakyi, Michael Essien Li, Yuan Xie, Cai Xia Hlordzi, Vivian 出版年：2020; Skin and intestinal mucosa lymphoid tissues are known to be the fish's first line of defence since they serve as the first point of contact for pathogens. Only few studies have investigated the influence of host-associat...

Comprehensive identification and profiling of Nile tilapia (Oreochromis niloticus) microRNAs response to Streptococcus agalactiae infection through high-throughput sequencing: FISH & SHELLFISH IMMUNOLOGYWang, Bei Gan, Zhen Cai, Shuanghu Wang, Zhongliang Yu, Dapeng Lin, Ziwei Lu, Yishan Wu, Zaohe Jian, Jichang 出版年：2016; MicroRNAs are a kind of small non-coding RNAs that participate in various biological processes. Deregulated microRNA expression is associated with several types of diseases. Tilapia (Oreochromis niloticus) is an importan...

Immunostimulatory effects of artificial feed supplemented with a Chinese herbal mixture on Oreochromis niloticus against Aeromonas hydrophila: FISH & SHELLFISH IMMUNOLOGYTang, Jufen Cai, Jia Liu, Ran Wang, Jiamin Lu, Yishan Wu, Zaohe Jian, Jichang 出版年：2014; The effects of a Chinese herbal mixture (CHM) composed of astragalus, angelica, hawthorn, Licorice root and honeysuckle on immune responses and disease resistant of Nile tilapia (Oreochromis niloticus GIFT strain) were i...

Molecular and functional characterization of CD59 from Nile tilapia (Oreochromis niloticus) involved in the immune response to Streptococcus agalactiae: FISH & SHELLFISH IMMUNOLOGYGan, Zhen Wang, Bei Zhou, Wei Lu, Yishan Zhu, Weiwei Tang, Jufen Jan, JiChang Wu, Zaohe 出版年：2015; CD59, the major inhibitor of membrane attack complex, plays a crucial role in regulation of complement activation. In this paper, a CD59 gene of Nile tilapia, Oreochromis niloticus (designated as On-CD59) was cloned and ...

NK-lysin from Oreochromis niloticus improves antimicrobial defence against bacterial pathogens: FISH & SHELLFISH IMMUNOLOGYHuang, Yu Zheng, Qi Niu, Jinzhong Tang, Jufen Wang, Bei Abarike, Emmanuel Delwin Lu, Yishan Cai, Jia Jian, Jichang 出版年：2018; NK-lysin, an effector of cytotoxic T cells and natural killer cells, is a potent antimicrobial peptide widely distributed in mammals. Homologues of NK-lysin have been discovered in several teleost species, but only sever...

Conservation of structural and interactional features of CD28 and CD80/86 molecules from Nile tilapia (Oreochromis niloticus): FISH & SHELLFISH IMMUNOLOGYHuang, Yu Wang, Zhiwen Zheng, Qi Tang, Jufen Cai, Jia Lu, Yishan Jian, Jichang 出版年：2018; Interaction of CD28 with CD80 or CD86 molecules provides a costimulatory signals required in T cell activation. In this study, we cloned and analyzed a CD28 gene (On-CD28) and a CD80/86 gene (On-CD80/86) from Nile tilapi...

In vivo assessment of the probiotic potentials of three host -associated Bacillus species on growth performance, health status and disease resistance of Oreochromis niloticus against Streptococcus agalactiae: AQUACULTUREKuebutornye, Felix K. A. Tang, Jufen Cai, Jia Yu, Huang Wang, Zhiwen Abarike, Emmanuel Delwin Lu, Yishan Li, Yuan Afriyie, Gyamfua 出版年：2020; Four weeks feeding trial was conducted to assess the in vivo probiotic potentials of three host-associated Bacillus species in O. niloticus. The fish were divided into five treatment groups and fed with diets containing ...

Transcriptome analysis of immune-related gene expression in hybrid snakehead (Channa maculata female x Channa argus male) after challenge with Nocardia seriolae: FISH & SHELLFISH IMMUNOLOGYChen, Jianlin Li, Yanqun Wang, Wenji Xia, Liqun Wang, Zhiwen Hou, Suying Huang, Jiahui Lu, Yishan 出版年：2018; Hybrid snakehead fish (Channa maculata female x Channa cups male), a new species used in freshwater aquaculture in China, is the common host of an epizootic bacterial infection by Nocardia seriolae. However, the informat...

卵形鲳鲹结节病病原的分离与鉴定: 《广东海洋大学学报》黄郁葱简纪常吴灶和鲁义善余坦健出版年：2008; 从湛江港、阳江闸坡海水网箱养殖的患结节病卵形鲳鲹(Trachinotus ovatus)中分离一株细菌,回归感染结果证明该菌是引起卵形鲳鲹结节病的病原,对卵形鲳鲹半致死浓度为45 g-1。该菌株呈革兰阳性,好氧,具有弱抗...; 关键词：卵形鲳鲹结节病诺卡氏菌 16S rDNA 被引量：29

复方中草药对吉富罗非鱼生长及肠道菌群的影响: 《广东海洋大学学报》汤菊芬吴灶和简纪常鲁义善王蓓出版年：2009; 将A、B、C三种复方中草药分别按质量分数1.5%的比例添加到罗非鱼商品饲料中,喂养初始体重约16.58±0.48g的吉富罗非罗28d,通过测定罗非鱼的增重率、饲料系数、肠道菌群等指标,研究三种复方中草药制剂对罗非鱼生长性...; 关键词：中草药吉富罗非鱼生长肠道菌群 被引量：26

Lactic acid bacteria, Enterococcus faecalis Y17 and Pediococcus pentosaceus G11, improved growth performance, and immunity of mud crab (Scylla paramamosain): FISH & SHELLFISH IMMUNOLOGYYang, Qiuhua Lu, Yongling Zhang, Ming Gong, Yi Li, Zhongzhen Ngoc Tuan Tran He, Yuyong Zhu, Chunhua Lu, Yishan Zhang, Yueling Li, Shengkang 出版年：2019; Mud crabs (Scylla paramamosain), a commercially important cultured species in the southeastern region of China, is usually infected by Vibriosis or parasites, causing great economic losses in cultured farms. Previous stu...

Identification and characterization of tumor necrosis factor receptor (TNFR)-associated factor 3 from humphead snapper, Lutjanus sanguineus: FISH & SHELLFISH IMMUNOLOGYCai, Jia Xia, Hongli Huang, Yucong Tang, Jufen Jian, Jichang Wu, Zaohe Lu, Yishan 出版年：2015; Tumor necrosis factor receptor (TNFR)-associated factor 3(TRAF3) is a key regulator in TNFR and Toll-like receptor (TLRs)/RIG-I-like receptors (RLRs) signal pathway. Here, a TRAF3 gene (Ls-TRAF3, GenBank Accession No: Kj...

Integrated analysis neurimmiRs of tilapia (Oreochromis niloticus) involved in immune response to Streptococcus agalactiae, a pathogen causing meningoencephalitis in teleosts: FISH & SHELLFISH IMMUNOLOGYWang, Bei Gan, Zhen Wang, Zhongliang Yu, Dapeng Lin, Ziwei Lu, Yishan Wu, Zaohe Jian, Jichang 出版年：2017; MicroRNAs (miRNAs) are a class of noncoding RNA molecules and play important roles in a wide spectrum of biological processes, including in immune response. Recent years have witnessed considerable amount of research int...

Development of DNA vaccines encoding ribosomal proteins (RplL and RpsA) against Nocardia seriolae infection in fish: FISH & SHELLFISH IMMUNOLOGYChen, Jianlin Chen, Zhenwei Wang, Wenji Hou, Suying Cai, Jia Xia, Liqun Lu, Yishan 出版年：2020; Nocardia seriolae, a Gram-positive pathogen, has been identified as the causative agent of fish nocardiosis. DNA vaccination has been proven to be effective in conferring protection against bacterial infection in fish. T...

Modulation of nutrient utilization, growth, and immunity of Nile tilapia, Oreochromis niloticus: the role of probiotics: AQUACULTURE INTERNATIONALKuebutornye, Felix K. A. Abarike, Emmanuel Delwin Sakyi, Michael Essien Lu, Yishan Wang, Zhiwen 出版年：2020; The production of Nile tilapia, Oreochromis niloticus, over the last few years has increased due to the adoption of intensive farming technologies. However, the continuous increase in O. niloticus production must be base...

Influences of immunostimulants on phagocytes in cultured fish: a mini review: REVIEWS IN AQUACULTUREAbarike, Emmanuel D. Kuebutornye, Felix K. A. Jian, Jichang Tang, Jufen Lu, Yishan Cai, Jia 出版年：2019; Lower vertebrates like fish mostly depend on innate immunity as the first line of defence against invading pathogens. One of the defence mechanisms in innate immunity for fish is the use of phagocytic cells such as monoc...

Molecular and functional characterization of peptidoglycan-recognition protein SC2 (PGRP-SC2) from Nile tilapia (Oreochromis niloticus) involved in the immune response to Streptococcus agalactiae: FISH & SHELLFISH IMMUNOLOGYGan, Zhen Chen, Shannan Hou, Jing Huo, Huijun Zhang, Xiaolin Ruan, Baiye Laghari, Zubair Ahmed Li, Li Lu, Yishan Nie, Pin 出版年：2016; PGRP-SC2, the member of PGRP family, plays an important role in regulation of innate immune response. In this paper, a PGRP-SC2 gene of Nile tilapia, Oreochromis niloticus (designated as On-PGRP-SC2) was cloned and its e...

中草药复合益生菌制剂对凡纳滨对虾生长、抗病力及水质的影响: 《广东海洋大学学报》汤菊芬黄瑜蔡佳鲁义善吴灶和简纪常出版年：2015; 将枯草芽孢杆菌、纳豆芽孢杆菌、地衣芽孢杆菌等比例混合,制成芽孢杆菌制剂;将芽孢杆菌制剂与粪肠球菌、嗜酸乳杆菌等比例混合制成复合益生菌制剂;将分别用3种芽孢杆菌发酵的中草药等比例混合制成中草药芽孢杆菌制剂;将分别用5种益生...; 关键词：凡纳滨对虾饲料添加剂益生菌制剂中草药复合制剂生长水质抗病力 被引量：20

Characterization of a tandem-repeat galectin-9 from Nile tilapia (Oreochromis niloticus) involved in the immune response against bacterial infection: FISH & SHELLFISH IMMUNOLOGYNiu, Jinzhong Huang, Yu Li, Yuan Wang, Zhiwen Tang, Jufen Wang, Bei Lu, Yishan Cai, Jia Jian, Jichang 出版年：2019; Galectin-9 is a < beta > -galactoside-binding lectin which could modulate a variety of biological functions including recognition, aggregation and clearance of pathogen. In this study, a galectin-9 homologue (OnGal-9) wa...

Cloning, expression of Vibrio alginolyticus outer membrane protein-OmpU gene and its potential application as vaccine in crimson snapper, Lutjanus erythropterus Bloch: JOURNAL OF FISH DISEASESCai, S. H. Lu, Y. S. Wu, Z. H. Jian, J. C. 出版年：2013; The outer membrane proteins of the marine aquatic animal pathogen, Vibrio alginolyticus, play an important role in the virulence of the bacterium and are potential candidates for vaccine development. In this study, the g...

卵形鲳鲹主要病害及其研究进展: 《安徽农学通报》夏立群黄郁葱鲁义善出版年：2012; 综述了卵形鲳鲹养殖中常见的病原性疾病8种,其中病毒病1种,细菌病4种,寄生虫病3种;并对这8种疾病的病原体、发病症状、防治手段以及近年来的研究进展分别进行了详尽的论述;进而归纳了卵形鲳鲹常见疾病的综合防治措施,提出了未来...; 关键词：卵形鲳鲹病害综合防治 被引量：18

Identification of common antigens of three pathogenic Nocardia species and development of DNA vaccine against fish nocardiosis: FISH & SHELLFISH IMMUNOLOGYChen, Jianlin Tan, Wanchun Wang, Wenji Hou, Suying Chen, Guoquan Xia, Liqun Lu, Yishan 出版年：2019; Fish nocardiosis is a chronic granulomatous bacterial disease and three pathogens have been reported so far, including Nocardia asteroids, N. seriolae and N. salmonicida. However, the absence of antigen markers is a bott...

Immune response in Lutjanus erythropterus induced by the major outer membrane protein (OmpU) of Vibrio alginolyticus: DISEASES OF AQUATIC ORGANISMSCai, Shuang-Hu Yao, Shao-Yun Lu, Yi-Shan Wu, Zao-He Jian, Ji-Chang Wang, Bei 出版年：2010; The outer membrane proteins (OMPs) of the marine aquatic animal pathogen Vibrio alginolyticus play an important role in the virulence of the bacterium and are potential candidates for vaccine development. In this study, ...

方斑东风螺吻管水肿病病原菌的初步研究: 《渔业现代化》黄郁葱简纪常吴灶和鲁义善王蓓出版年：2009; 从患病方斑东风螺(Babylonia areolata)分离到一株致病菌Balo001,运用生理生化方法并结合分子生物学方法对病原菌进行分类鉴定,并对病原菌进行药敏分析及半致死剂量(LD50)测定。结果表明:致病菌Ba-...; 关键词：方斑东风螺吻管水肿病哈氏弧菌 被引量：17

Comparison of protective efficacy between two DNA vaccines encoding DnaK and GroEL against fish nocardiosis: FISH & SHELLFISH IMMUNOLOGYChen, Jianlin Wang, Wenji Hou, Suying Fu, Weixuan Cai, Jia Xia, Liqun Lu, Yishan 出版年：2019; Fish nocardiosis is a chronic granulomatous bacterial disease mainly caused by three pathogenic bacteria, including Nocardia seriolae, N. asteroids and N. salmonicida. Molecular chaperone DnaK and GroEL were identified t...

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